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Chronic Fatigue Syndrome (CFS): The Regulation Medicine and Neural Therapy Approach

Dr. Hüseyin Nazlıkul
Dr. Hüseyin Nazlıkul 14.01.2026 4 min read
Chronic Fatigue Syndrome (CFS): The Regulation Medicine and Neural Therapy Approach

Chronic Fatigue Syndrome (CFS) is a complex disease that seriously affects individuals' quality of life, presenting with symptoms such as prolonged, excessive fatigue, musculoskeletal pain, sleep disorders, cognitive dysfunction, and immunological imbalances. Although its cause is not fully understood, factors such as infections, immune system disorders, oxidative stress, and mitochondrial dysfunction are thought to play a role.

Regulation medicine and Neural Therapy offer a powerful tool for both symptomatic improvement and achieving systemic balance by targeting the interference fields underlying this condition. In addition, a treatment strategy combined with antioxidants and nutritional supplements can play an important role in managing CFS.

The Role of Neural Therapy in Regulation Medicine

Regulation medicine is a holistic approach aimed at activating the body's own capacity for self-healing. Neural therapy aims to regulate the autonomic nervous system through injections of local anesthetics. With this method:

Identifying and Treating Interference Fields:

Interference fields are frequently observed in CFS. In particular, chronic infections (e.g., sinusitis, tonsillitis), old surgical scars, dental foci, and intestinal dysbiosis can create persistent stress in the nervous system, triggering CFS symptoms. Regulating these areas with neural therapy can provide significant symptomatic relief for patients.

Regulation of the Autonomic Nervous System:

Neural therapy reduces the stress burden by re-establishing sympathetic-parasympathetic balance. This balance has particularly positive effects on energy metabolism and immune system functions.

The Role of Oxidative Stress and Nutrition

Oxidative stress and mitochondrial dysfunction are among the important causes of fatigue in CFS. Mitochondria are at the center of energy production and are vulnerable to oxidative damage in this process. A nutritional approach supported by antioxidants plays a critical role in reducing oxidative stress and optimizing energy production.

Critical Nutrients and Supplements

NADH (Nicotinamide Adenine Dinucleotide): NADH is necessary for mitochondrial energy production and raises cellular energy levels by increasing ATP synthesis. Research shows that NADH supplementation reduces fatigue and improves cognitive function.

Coenzyme Q10 (CoQ10): CoQ10 plays a critical role in the mitochondrial electron transport chain. Thanks to its antioxidant properties, it reduces oxidative damage and supports energy metabolism. CoQ10 levels have been found to be low in CFS patients, so supplementation is recommended.

Vitamin C: A powerful antioxidant, vitamin C supports the immune system and neutralizes the effects of free radicals. It can also accelerate tissue healing by contributing to collagen synthesis.

Vitamin B3 (Niacin): Niacin is a precursor molecule for NADH production. It is beneficial in easing fatigue symptoms by supporting mitochondrial energy production.

Zinc and Selenium:

  • Zinc is an important mineral that regulates immune function and helps reduce oxidative stress.
  • Selenium, as a component of the glutathione peroxidase enzyme, reduces free radical damage and supports thyroid function.

Omega-3 Fatty Acids: Provides stability to cell membranes and reduces inflammation. Supports brain function, providing improvement in cognitive symptoms.

Nutrition and Lifestyle Recommendations

Anti-inflammatory Diet:

  • Processed foods should be avoided; vegetables, fruit, healthy fats, and high-quality proteins should be consumed.
  • Sugar and refined carbohydrates should be limited, as they can increase inflammation.

Intestinal Health:

  • Probiotic and prebiotic support is important for correcting intestinal dysbiosis and supporting the immune system.
  • Intestinal permeability frequently plays a role in CFS; therefore, a gluten-free diet may be beneficial for some patients.

Hydration:

  • Adequate water intake is necessary for cellular detoxification and energy production.

Regular Light Exercise:

• Excessive exertion can increase fatigue; therefore, low-intensity activities (e.g., yoga, light walking) should be preferred.

Conclusion

Chronic Fatigue Syndrome is a multifactorial and complex disease that requires a multidisciplinary approach to treatment. Neural therapy offers a powerful tool for regulating the autonomic nervous system by targeting interference fields. This approach can achieve more effective results when combined with nutritional support and antioxidants. Critical nutrients such as NADH, CoQ10, vitamin C, B3, zinc, and selenium support mitochondrial function by reducing oxidative stress and help ease symptoms.

With a holistic approach, it is possible to improve the quality of life of CFS patients and achieve functional recovery. For this reason, individualized treatment protocols should be created based on personal needs.

Dr. Hüseyin Nazlikul, M.D., PhD.
President of IFMANT, BNR, MTAR
Specialist in General Medicine - Medical Biophysics

President of IFMANT (International Federation of Medical Associations of Neural Therapy)
President of the Turkish Neural Therapy Society
President of the Turkish Manual Medicine - Pain Regulation Association
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Tel: 0 (212) 219 19 12 or 219 09 00 Fax: 0 (212) 219 18 38